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Multiple system atrophy (MSA)
Symptoms of multiple system atrophy (MSA)

The main symptom of multiple system atrophy (MSA) is losing control of muscles in the body. This happens gradually in some people and quickly in others.

MSA affects people in different ways, depending on which muscles are affected. Some of the most common symptoms include:

  • bladder problems, such as needing to pee more often or being unable to pee
  • feeling dizzy and faint when standing up
  • erectile dysfunction (impotence)
  • slow, clumsy or unsteady movement
  • slurred speech
  • stiff, tense muscles that may be painful

It can also cause a wide range of other symptoms, such as:

  • feeling too hot or too cold
  • trouble sleeping
  • noisy breathing, unintentional sighing and snoring
  • finding it difficult to chew or swallow
  • constipation (finding it hard to poo)
  • unpredictable laughing or crying

The symptoms of MSA most often begin in people over 50 years old. It does not usually affect people under 30 years old.

See a GP if:

  • you think you have symptoms of multiple system atrophy (MSA)

Important

Some of these symptoms are very common and can be caused by many different conditions.

Having them does not definitely mean you have multiple system atrophy (MSA). But it's important to get them checked by a GP.

How multiple system atrophy (MSA) is diagnosed

If a GP thinks you have symptoms of multiple system atrophy (MSA) or a similar condition, they'll usually refer you to a brain and nerve specialist in hospital (neurologist).

A neurologist may diagnose MSA based on your symptoms, how long you've had them and how quickly they're getting worse.

You may need some tests first to investigate your symptoms and what could be causing them.

It can be difficult to diagnose MSA, as there's no specific test for it.

In the early stages, the symptoms can also be very similar to other conditions such as Parkinson's disease.

Treatments for multiple system atrophy (MSA)

There's currently no cure for multiple system atrophy (MSA) and no treatments that can stop it getting worse.

But treatment and support is available to manage any symptoms and help you stay comfortable and independent for as long as possible.

You'll be supported by a team of healthcare professionals who will help to create a care plan.

For example, you may be offered medicines for sleep problems or dizziness, and speech therapy can help with swallowing and communication problems.

Physiotherapy and occupational therapy may also be recommended. This is to help you maintain fitness and muscle strength and make your daily life easier.

Every person's needs will be different depending on their symptoms.

How multiple system atrophy (MSA) affects your life

Multiple system atrophy (MSA) affects how long someone lives and can sometimes get worse quickly.

Most people eventually need some help and support with their daily living.

The type of support and how quickly it's needed can vary, as MSA affects everyone differently.

If you're diagnosed with MSA, your care team will be able to discuss how your condition may affect you or your family.

Causes of multiple system atrophy (MSA)

In people with MSA, nerves in the area of the brain that controls things like balance and movement become damaged and lost over time.

It's not known why this happens.

There's no evidence that it can be passed on to children by their parents (inherited).

Research is continuing to look at whether some people are more at risk of having the condition.

Help and support for multiple system atrophy (MSA)

If you have multiple system atrophy (MSA), healthcare professionals will be there to support you throughout your treatment.

You may also find it helpful to contact the MSA Trust, a charity that supports people with MSA.

If you or someone you know needs help with day-to-day living because of illness or disability, find out about social care and support options.

The MSA Trust

The MSA Trust are a charity that provides a range of support and information for people affected by SMA.

Last Reviewed
06 March 2025
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MSN & Lunts Pharmacy Group
30 Great Bridge, Tipton
West Bromwich
West Midlands
DY4 7EW

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