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Guillain-Barré syndrome
Symptoms of Guillain-Barré syndrome

Guillain-Barré syndrome affects your senses, your movement and things such as breathing and your heartbeat.

It usually affects your arms and legs first before you get symptoms in other parts of your body.

Symptoms usually get worse over the first 2 to 4 weeks.

You might feel tingling, numbness or pins and needles in your feet and hands first. This is usually followed by muscle weakness and difficulty moving your joints.

Other symptoms can include:

  • sharp, shooting pain (nerve pain), often in your legs or back
  • problems breathing
  • problems with your face, such as drooping face muscles or trouble swallowing or speaking
  • problems with your eyes, such as double vision

Some people’s symptoms become so severe that they are not able to move their legs, arms and face (paralysis).

Ask for an urgent GP appointment or get help from NHS 111 if:

  • you think you have Guillain-Barré syndrome

You can call 111 or get help from 111 online.

Important

Some of the symptoms are common and may be caused by another condition.

Having these symptoms does not definitely mean you have Guillain-Barré syndrome. But it's important to get medical help so your symptoms can be checked.

Call 999 or go to A&E if:

  • you have problems with your face muscles, such as one side of your face drooping (falling lower than the other side) or trouble swallowing
  • you’re not able to lift one or both arms
  • you have trouble speaking, such as slurring your words

These could be signs of a stroke and need urgent medical attention.

Do not drive to A&E. Ask someone to drive you or call 999 and ask for an ambulance.

Bring any medicine you take with you.

How Guillain-Barré syndrome is diagnosed

If you have symptoms of Guillain-Barré syndrome, your GP will check your reflexes and will check for any numbness or weakness in your muscles.

If a GP thinks you could have Guillain-Barré syndrome, they'll refer you to a specialist in nerve conditions (neurologist) for tests and treatment. You may have tests such as:

  • an electrical test of your nerves and muscles
  • a breathing test (spirometry)
  • blood tests
  • a lumbar puncture, where a sample of fluid is taken from the spine for testing
Treatments for Guillain-Barré syndrome

If you've been diagnosed with Guillain-Barré syndrome, you'll be treated in hospital straight away. You'll usually be in hospital for several weeks. Some people may need to stay for several months.

Your main treatment will be immunotherapy to stop your immune system from attacking your nerves. You'll either have intravenous immunoglobulin (IVIG) or plasma exchange.

You'll also have treatment to help manage your symptoms and monitor your condition. You might need:

Recovering from Guillain-Barré syndrome

You may be in hospital for several months while you have treatment and recover from Guillain-Barré syndrome.

Most people will be able to walk within 6 months and will recover within a year.

Some people continue to have longer-term problems such as:

  • tingling in the hands and feet
  • sharp, shooting pain (nerve pain)
  • feeling exhausted (fatigue)
  • muscle pain and muscle weakness
  • being unable to walk without help
  • anxiety and depression

You may be offered:

  • physiotherapy to treat muscle stiffness and help you to move more easily
  • occupational therapy to help you manage everyday tasks and go back to work

Your doctor will check you every few months after you recover. You'll then have checks once a year, because some people can become unwell again and need more treatment.

Guillain-Barré syndrome can be life-threatening and cannot always be cured. The chance of dying is higher in older people or people who have had severe symptoms.

Contact your specialist straight away if:

  • you have long-term symptoms that are getting worse
  • you've recovered from Guillain-Barré syndrome and you start having symptoms again
How you get Guillain-Barré syndrome

It's not known what causes Guillain-Barré syndrome, but it's thought to be caused by problems with the immune system.

It usually starts within a few weeks of an infection, such as flu or a stomach bug.

When you get an infection, your immune system normally attacks and kills the bacteria or virus. But in Guillain-Barré syndrome the immune system starts to attack your nerves.

Guillain-Barré syndrome can affect anyone, but it's more common in adults and males.

Support if you have Guillain-Barré syndrome
Get help from NHS talking therapies

Having Guillain-Barré syndrome can affect your mental health. It might help to talk about how you're feeling.

You can access talking therapies for free on the NHS. These services can help you find ways to cope.

Help is available in person, by video, over the phone or as an online course.

Support from charities

You can also get support from charities such as Guillain-Barré & Associated Inflammatory Neuropathies (GAIN).

Last Reviewed
26 March 2025
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MSN & Lunts Pharmacy Group
30 Great Bridge, Tipton
West Bromwich
West Midlands
DY4 7EW

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